Tolerance loss in diabetics: association with foreign antigen exposure
We read with interest the article by Dr Lawlor’s group relating milk avoidance to insulin resistance [1]. Cow’s milk has also been causally associated with Type 1 diabetes [2]. However, the pathogenic basis of these associations remains unclear. We hypothesize that the possible role of cow dairy in causing/ accentuating the diabetic state could be due to a loss of oral tolerance leading to a burden on the individual’s immune defense systems. Data in support of this hypothesis are presented below.